Travel Edition  
May 2008  


We are delighted to announce that INDOOR Biotechnologies has recently signed a license agreement with Sanquin Blood Supply Foundation (Amsterdam, The Netherlands) for allergen-specific monoclonal antibodies produced by Dr. Rob Aalberse. Under this agreement, INDOOR Biotechnologies has acquired exclusive, worldwide rights to a unique panel of monoclonal antibodies to dust mite, cat, dog and pollen allergens that will strengthen its product portfolio and commercial activities. Both parties will derive significant benefits from this cooperative license agreement.

Over the next two weeks, Indoor Biotechnologies will exhibit at the American Industrial Hygiene Conference and Exhibition (AIHCE) in Minneapolis and at the European Academy of Allergy and Clinical Immunology (EAACI) annual meeting in Barcelona, Spain. These excellent meetings allow us to serve the indoor air quality, allergy and immunology fields. We look forward to meeting you at our exhibits and research presentations.

The Final Program for our training course on indoor allergens has just been released. With its focus on state-of-the-art multiplex technology for allergen detection (MARIA¢â), this course will cover exciting new approaches to exposure assessment for research studies, IAQ investigations and commercialization. Please Register Now before the August 1st deadline.

in this issue
  • Health Effects of Indoor Allergens - Final Program, September 8-10, 2008
  • Upcoming Scientific Meetings
  • New LoTox¢â Low Endotoxin Purified Allergens
  • Mite Serine Proteases
  • Multiplex ARray for Indoor Allergens (MARIA¢â)

  • Upcoming Scientific Meetings

    AIHCE in Minneapolis.

    American Industrial Hygiene Conference and Exposition (AIHCE), June 1-4, Minneapolis, MN, Exhibit No. 1324.

    Dr. Eva M King: Multiplex Technologies - Expanding Horizons for Quantitative Allergen Exposure Assessment.
    Session PO119, Mold and Water Damage in Buildings. Tuesday June 3, 2:00 pm - 5:20 pm, Center L100 E

    Posters: S Filep et al, Performance Data for a Dust Collection Device...
    Session PS401, Monday, June 2, 10:00-12:00

    A Tsay et al, Universal Standard for Allergen Exposure Assessment
    Session PS403, Tuesday, June 3, 10:00-12:00

    See us also at:

    Indoor Air Quality Association 11TH Annual Meeting, Booth 303 Tampa Convention Center Tampa, FL June 12-14, 2008

    EAACI in Barcelona

    European Academy of Allergology and Clinical Immunology (EAACI), Barcelona, Spain, June 7-12, Exhibit Number 10.

    Workshop 17 - Allergen Immunobiology and Vaccine Development Monday, 9 June 2008, 13.30 to 15.00 (E1).
    Anna Pomes, PhD: Lessons learned from cockroach allergen structure and function.


    No. 77: Chrusczc et al: X-ray crystal structures of mite allergens, Der f 1 and Der p 1, reveal differences in surface exposed residues that may be related to antibody binding.
    No. 749: Wunschmann et al: Expression of a deglycosylated recombinant Fel d 1 in Pichia pastoris
    No. 1085: King et al.: Performance Evaluation of Allergen Exposure Assessment using Multiplex Fluorescent Array Technology- Design of A Multi-Center Ring Trial
    No. 1520: Filep et al: Purified Standard for Allergen Analysis modeled on the EU CREATE Study

    New LoTox¢â Low Endotoxin Purified Allergens

    Tired of dealing with endotoxin? Our LoTox¢â purified allergen product line is specifically designed to meet the needs of researchers who need low endotoxin products e.g. in sensitive cell culture systems. LoTox¢â allergens are highly purified and contain <0.03EU/¥ìg protein. We have recently added three new allergens to the LoTox¢â product line: nDer p 2, nFel d 1 and rFel d 1 (deglycosylated). Custom LoTox¢â services are also available.

    Mite Serine Proteases

    In response to interest in the enzymatic activity of mite allergens, we have developed a new research reagent: purified natural Serine Proteases from D. pteronyssinus (Code: NA-DPSP-2). The serine proteases are purified from mite culture by benzamidine affinity chromatography and are quantified for enzyme activity. This product may be useful for studies on airway inflammation, asthma, protease activated receptors (PARs), and mouse models of asthma.

    Multiplex ARray for Indoor Allergens (MARIA¢â)
    Old Brewery building, Warminster

    MARIA¢â combines Indoor Biotechnologies allergen-specific monoclonal antibodies with the power of Luminex xMAP¢ç technology to measure eight allergens at once in a single test. MARIA¢â provides improved assay performance (increased sensitivity, accuracy and precision) in a high throughput system with substantial time and cost savings.

    We have also developed a Universal Allergen Standard for use in both MARIA¢â and ELISA systems. This standard comprises eight purified allergens with protein content based on amino acid analysis, as per the European Union CREATE allergen standardization recommendations.

    MARIA¢â technology was developed in collaboration with Radix Biosolutions and Luminex Corporation, with support from a Small Business Innovation Research contract from the National Institutes of Environmental Health Sciences (NIEHS).

    MARIA¢â kits and services are available exclusively through Indoor Biotechnologies. To learn more about MARIA¢â, visit our website and Register Online for our training course in September.

    Health Effects of
    Indoor Allergens -
    Final Program, September 8-10, 2008

    The Final Program for our comprehensive training course on "Health Effects of Indoor allergens, Molds and Endotoxin - Theory and Practice" is now available. The program includes:

    • Distinguished guest speakers on allergens, asthma and molds - world leaders in the field.
    • Informal seminar style lectures
    • Hands on wet lab training in allergen analysis by ELISA and MARIA¢â.
    • Cutting edge approaches to allergen exposure assessments.

    This year the program features multiplex array technology for allergen detection (MARIA¢â). Participants will be the first to gain hands-on experience of this powerful technology for allergen exposure assessment.

    Join us in Charlottesville, September 8-10, 2008. The conference is limited to 40 participants. Please Register Online to reserve your place(s) as soon as possible. The deadline for Early Registration (10% discount) is August 1st.