Grants

Indoor Biotechnologies research on allergen structure and function and on new enabling technologies for environmental allergen detection has been funded by grants from the National Institutes of Health, the European Union, government agencies and research foundations.

?Research on the Ventia™ rapid test for dust mite and, most recently, on fluorescent multiplex array technology for indoor allergens (MARIA™) was funded in part by Small Business Innovation Research (SBIR) awards from the National Institute for Environmental Health Sciences (ES011920 and ES55545C, respectively).

  Indoor Biotechnologies Ltd participated in the 5th Framework Programme of the? European Union CREATE project to develop purified allergen standards and to compare sensitivity, specificity and reproducibility of ELISA measurements for allergens (Contract G6RD-CT-2001-00582)

?Dr. Pomes has recently been awarded a grant by the National Institute of Allergy and Infectious Diseases (NIAID) to support research on allergen structure.? The aims of this research are to determine the structures of major mite and cockroach allergens and allergen antibody complexes by X-ray crystallography.? The structure of antibody binding epitopes will be defined and site-directed mutagenesis will be used to identify IgE binding sites.? Mutants will also be analyzed for T cell responses in mite or cockroach allergic patients.? This research aims to develop hypoallergenic variants of allergens that may be used in new forms of allergen immunotherapy (AI077653).